Use Ajax '95 4-3-3.
When your team is losing by any amount of margin, play a 1-2-5-2. When attacking, your team will go up in 7s making your opposition defend deeper, causing them to make a mistake about 95% of time.
Hint: Best performances:
To get the best from your players, play them in their preferred position. For example, Thuram is a right back but can play in centre back. Play him in right or centre.